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Parada LF, Land H, Weinberg RA, Wolf D, Rotter V (1984) Cooperation between geneencoding p53 tumour antigen and ras in cellular transformation. In the second stage, performed several dayslater, the surgeon removed the anus, the ischiorectal fat, the levators, the rectum, and atleast a portion of the mesorectum up to the level of the promontory.2 This operation had 2flaws: (1) it did not remove the lymph nodes located along the superior rectal vessels, and(2) it left a portion of colon and mesocolon attached to the distal limb of the stoma, whichoften resulted in a chronic perineal sinus.

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